When the positive blood culture starts, conventional S. Therefore, rapid and accurate discrimination of MRSA from MSSA is essential for clinical diagnosis to facilitate a specific antimicrobial therapy ( Srisrattakarn et al. Furthermore, empirical anti-MRSA treatment for MSSA bacteremia can lead to poor outcomes compared with standard therapy ( Jones et al. Vancomycin use is associated with increased antimicrobial and monitoring costs and may bring about drug-induced acute kidney injury in up to 15% of patients ( Pritchard et al. aureus (MRSA) bacteremia stay longer in hospitals and generate higher costs than those with bacteremia caused by methicillin-susceptible S. aureus infections are particularly problematic due to the frequent antibiotic resistance, among which methicillin resistance is the most clinically relevant ( Turner et al. aureus bloodstream infections (BSI) ( Asgeirsson et al. High mortality rates from 20% to 50%, frequent recurrences from 5% to 10%, and lasting impairment in more than one-third of the survivors characterize S. Staphylococcus aureus (SA) is a leading cause of bacteremia. The rapidity and simplicity of results generated by these methods have the potential to improve patient outcomes and aid in the prevention of the emergence and transmission of MRSA. aureus (MRSA), and the Accelerate Pheno TM system can also provide antimicrobial susceptibility testing (AST) results. Furthermore, BioFire FilmArray and Xpert MRSA/SA identify methicillin-resistant S. aureus in positive blood cultures or direct blood samples.

These rapid and simple methods can rapidly identify S. The following methods were included: (a) Hybrisep in situ hybridization test, (b) T2Dx system, (c) BinaxNow Staphylococcus aureus and PBP2a, (d) Gram staining, (e) PNA FISH and QuickFISH, (f) Accelerate Pheno TM system, (g) MALDI-TOF MS, (h) BioFire FilmArray, (i) Xpert MRSA/SA. A literature review focusing on rapid and simple methods for diagnosing S. However, it needs well-trained personnel, and costs are high. An amplification assay such as real-time PCR is a sensitive, specific technique to detect S. Staphylococcus aureus is an important causative pathogen of bloodstream infections.

Gram negative staphylococcus